The (metabolic) 'cost of life': New method quantifies hidden energy costs of maintaining metabolic pathways

There are "costs of life" that mechanical physics cannot calculate. A clear example is the energy required to keep specific ...
eLife

PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...