The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

In 1931, physicists Knoll and Ruska unveiled the first electron microscope, revolutionizing science by using magnetic lenses ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron—an object traveling so fast it could circle the Earth many times in a matter of a second. Researchers at ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...

QIScope: When imaging low protein levels in live cells on the high-sensitivity QIScope, bioluminescence (blue) significantly outperforms fluorescence (green). (Courtesy: Ruyu Ma - Helmholtz Munich) A ...