Single-cell analyses revealed molecular profiles that can distinguish PTSD from depression, potentially leading to better drugs for this psychiatric disorder. To test this hypothesis, Girgenti and his ...

A global consortium of scientists has created the first and most detailed "developmental maps" of the mammalian brain (from mouse to human) to date, taking the first critical steps in unraveling the ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

What unique processes conspire to create a healthy, functional human brain? How can we be so genetically similar to, say, chimpanzees, and yet be light-years more sophisticated cognitively and ...

In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and at the Allen Institute have created one of the most detailed maps of the mouse brain ...

Using single-nuclei RNA sequencing (snRNA-seq), scientists from Mass General Brigham, SUNY Upstate Medical University, and elsewhere have identified specific brain cell types in the hippocampus that ...

A groundbreaking study shows that two repurposed cancer drugs, when combined, can correct complex brain cell dysfunction and restore memory in Alzheimer’s mouse models, offering hope for new ...

At the turn of the 20th century, Korbinian Brodmann released one of the most consequential brain maps ever. By studying the humps, grooves, layers, and cells of the cortex—the outermost layer of the ...

In a new proteomics extravaganza, scientists have unearthed groups of proteins that appear to be at the heart of Alzheimer’s disease pathogenesis. As described in Cell on September 25, scientists led ...