Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...

Spatial biology first entered the omics scene about a decade ago. Since then, the technology has generated significant buzz both inside and outside of the lab—beyond its contributions to science. The ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Disrupted circadian rhythms from night shifts, irregular sleep schedules or frequently flying across time zones can fuel ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Scientists have identified a new CAF subset in HNSCC using tissue cytometry and spatial transcriptomics. In two-thirds of cases, head and neck squamous cell carcinomas (HNSCC) require treatment with ...