Figure 1: a, Secondary structure of E. coli 4.5S RNA and its interaction site with Ffh (shown in gray as two-domain model). Figure 2: NMR spectra of exchangeable protons of the SRP 28-mer. Some ...
Researchers test state-of-the-art models on diverse RNA structures, opening doors for RNA-based therapies and drug design Ribonucleic acid (RNA) is one of life’s most versatile molecules, with roles ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 30 (July 26, 2016), pp. 8430-8435 (6 pages) The predictive modeling and design of biologically active RNA ...
Complexes, such as protein/protein, nucleic acids/nucleic acid, protein/nucleic acid, protein/ligand, nucleic acid/ligand, are often difficult to crystallize even on well-defined biological systems, ...