The complement system is a recognized pillar of host defence against infection and noxious self-derived antigens. Complement is traditionally known as a serum-effective system, whereby the liver ...
Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...
Understanding rare genetic variants within the terminal pathway of complement system in preeclampsia
Preeclampsia (PE) is a common pregnancy-specific vascular disorder that affects approximately 3% of pregnancies [1, 2]. It accounts for over 50 000 maternal and 900 000 perinatal deaths annually [3, 4 ...
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