July 31, 2007 (New York, NY)-Serum levels of complement factors C3 and C4 were predictors of stroke risk over two years in a cohort of men referred for coronary angiography, with C4 emerging as ...

Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 14 (Jul. 15, 1989), pp. 5575-5579 (5 pages) ...

Complement activation is common in patients with systemic lupus erythematosus (SLE), resulting in hypocomplementemia and deposition of complement at sites of tissue damage. The availability of mice ...

There’s a clear sex bias in many diseases. Lupus, for instance, affects women nine times more often than it does men. Schizophrenia tends to be far more severe in males. But what’s behind the ...

Winning a rare insight into the cause of schizophrenia and possible ways to treat it, scientists in Boston say they have identified a biochemical pathway that contributes to the disease by altering ...

A new study published in the journal Nature has homed in on the sex-specific activity of a certain gene that both increases the risk of developing schizophrenia and decreases the risk of developing ...

A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person's risk of schizophrenia is increased if they inherit specific variants in a gene related to "synaptic ...